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Here's a deep look at how it works and whether it's worth trying. Weight loss cleanses are an extreme approach and come with potentially detrimental health effects. Because there are so many different kinds of cleanses, it’s difficult to pinpoint exactly which risks are greatest for each type of cleanse. Keep in mind that many of these health effects are likely to be seen with weight loss in general and not necessarily unique to the VLCD method.

"Detox diets can cause big fluctuations in blood sugar, which can be dangerous for people with diabetes," Beaver adds. "In addition, the high sugar content in some of these diets can lead to diarrhea, and severely limiting calories for an extended period of time can affect a woman's menstrual cycle and bone health." Most detox diets are severely lacking in protein and many B vitamins.

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