Small Molecule API Market 2022: Driving Factors, Business Strategies and Market Size Forecast to 2027

Market Overview

Market Research Future (MRFR) presumes that the Small Molecule API Market will be advancing at a rate of 7.0% from 2020 to 2027. Also, the total value by the end of 2027 is projected to be around USD 279,687.1 Million, believes Market Research Future.

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Top Companies

The top small molecule API developers are Mylan N.V., Allergan Plc, Sun Pharmaceutical Industries Ltd., Glaxosmithkline Plc, Aurobindo Pharma, Novartis AG, Albemarle Corporation, Cambrex Corporation, Pfizer Inc., Lonza, Teva Pharmaceutical Industries Ltd., Merck Sharp Dohme Corp., Dr. Reddy’s Laboratories Ltd, Siegfried AG, and more.

Small molecules find extensive use in the treatment of numerous conditions and diseases and are known for their diversity with respect to their mechanism of action. Given their appealing physicochemical characteristics as well as small size, they are effectively utilized as allosteric modifiers as well as enzyme inhibitors, are able to target extracellular proteins or intracellular receptors within the nuclei, cytosol, and central nervous system.

Market segment

By type

Biological procedures
Chemical process

By application

Ophthalmology
Cardiovascular
Metabolic
Dermatology
Respiratory
Urology
Autoimmune disease
Dermatology
Infectious
Immunology

By product

Contract
Captive

By geography

North America
Asia pacific
Europe
Latin America
Middle East

Top Drivers and Main Barriers

The small molecule API industry has turned extremely attractive in recent years, given the rising cases of several infectious and chronic diseases, along with the surge in the number of contract research manufacturers. The rise in drug discovery and development of various pharmaceuticals, growth of small molecule API, and extensive research development activities adds to the business worth too.

Small molecules’ use as API has been quite significant for the patients and the healthcare industry. Small molecules offer numerous benefits, especially compared to large molecule API. A small molecule is easily engineered to offer a robust therapeutic impact even with a tiny dose, which can be lower than 10 mg.

With the recent COVID-19 outbreak, the healthcare sector has been under massive pressure as the cases continue to rise worldwide. With the healthcare industry working on curbing the spread of the virus, rigid lockdown as well as movement restrictions have been enforced across countries. The development and operational process has been shut down temporarily while RD activities have been delayed as well. In addition, the pandemic has put a stop to clinical trials owing to stay-at-home orders and the healthcare workers’ rising focus on treating Covid-19 patients. These factors have been slightly unfavorable for the small molecule API market. But it is anticipated that the market size shall grow smoothly in the years ahead, as the pharmaceutical industry continues to thrive across the globe.

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Market Segmentation

Types of small molecules APIs are Synthetic/Chemical API as well as Biological API.

Top applications considered in the MRFR study are Oncology, Cardiovascular, Immunological Disorders, Diabetes, and more.

Manufacturing methods discussed in the report are In-House along with Contract.

Regional Insight

North America generates the highest revenues in the small molecule API market, landing the top position with the US, Mexico, and Canada as the major players. Huge spending on the pharmaceutical sector, surge in drug development as well as research activities will ensure continuous market growth in the years to come.

Asia Pacific is heading for incredible growth in the coming years, potentially gaining the fastest growth in the worldwide market. The low cost of small molecule API in the region and the possibility of developing a series of new products using these components will ensure tremendous business growth. The rapidly mounting number of API manufacturing facilities in China combined with the supportive Indian government schemes and policy like 100 percent FDI that attract international players for business expansion adds to the business worth as well.

Latest News

January 2022

Pharmaron Beijing Co. Limited has carried out the acquisition of Aesica Pharmaceuticals Limited from the Recipharm group. The company’s Cramlington Site in the United Kingdom boasts of extensive cGMP manufacturing services for a host of Active Pharmaceutical Ingredients, both pilot scale as well as commercial scale.