The Titans, as the No. 6 seed in the 2020 AFC playoffs, havealready knocked off the No. 3 Patriots and No. 1 Ravens on the road to get to (3:05 p.m. ET, CBS). Will they be able to pull off one more big upset at the No. 2 Chiefs?

Tenne see has a lot K.J. Osborn Jerseys of confidence as its running game powered by NFL rushing champion Derrick Henry and its defense have dominated to get the team on the brink of , 20 seasons after the franchise reached Super Bowl 34. But Kansas City, hosting the AFC title game for a second consecutive year,is also red-hot with quarterback Patrick Mahomes, having dropped 51 points in a 20-point big comeback victory over the Texans at home last week.

Here's everything to know about betting on in the NFL playoffs, including updated odds, trends and our prediction for the AFC championship game.

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Chiefs vs.Titans odds for AFC championship gameSpread:Chiefs by 7.5Point total:52.5Odds:Titans -120, Chiefs +100

The Chiefs have been hovering around touchdown favorites all week, as they're playing a much lower seed than expected and staying in Arrowhead Stadium. The point total has been higher, but is lowering close to kickoff.

Chiefs vs. Titans all-time series

The Chiefs lead the all time series 29-24, dating back to the time when the Titans were the Houston and Tenne see Oilers. Andy Reid's only Chiefs win over the Titans came in his first year with the team in October 2013 Jake Bargas Jerseys . The Titans have won four straight, including 22-21 in Kansas City inthe '18 wild-card playoffs and 35-23 in Nashville in the '19 regular season.

Three trends to know

The Titans are10-7-1 against the spread this season. The Chiefs are 12-5. 53 percent of spread bettors like the Chiefs while 66 Dalvin Cook Hoodies Sweatshirts percent of moneyline bettors like the Titans.

The Titans have seen the total go over in 10 of 18 games. The Chiefs' games have gone over only 9 times. 56 percent of bettors like this game to go under.

The Titans have won and covered in 7 of their past 9 games. The Chiefs have won and covered in 7 consecutive games, with their last lo s and non-cover happening in the lo s to the Titans on Nov. 10.

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Three things to watch

Andy Reid vs. Mike Vrabel

Reid hasn't fared well against several previous Titans coaches, including Jeff Fisher, Ken Whisenhunt and Mike Mularkey, going 1-8 in his career against them. Vrabel looks like the best of the bunch, as a Ron Yary Jerseys protege of another Reid nemesis, Bill Belcihick. Reid also has seen his teams struggle in championship game at 1-5 as he's gotten to only one Super Bowl with the Eagles. Reid can't be coaching tight here as Vrabel and his staff are crushing it.

Henry vs. the Chiefs' run defense

The Chiefs have been shaky in their front seven trying to stop the run all season, ranking No. 26 in the NFL during the regular season. They gave up 188 yards and 2 TDs on 23 carries to Henry in the first meeting. In his past three games after being rested for a hamstring injury in Week 16, Henry has rushed for 211, 182 and 195 yards. Although Kansas City might get a boost fromthe potential return of itsbest defensive lineman, Chris Jones (calf-questionable), Henry will remain Harrison Hand Jerseys a handful. The best way to stop him is jump out to a lead and make quarterback Ryan Tannehill throw often.

Travis Kelce vs. the Titans' tight end defense

The Titans were not effective in covering the tight end for most of the season despite having a ballhawk such as Kevin Byard at safety. Kelce, coming off a 10-catch, 134-yard, 3-TD game against the Texans, had 7 catches for 75 yards and a TD in the first meeting. Mahomes should see Kelce open for chunk gains again.

Stat that matters

The Titans couldn't cover Chiefs wide receiver Tyreek Hill in the first game, either. He had 11 catches for 157 yards as part of Mahomes' 446-yard day. The Chiefswill try to get Hill Isolated outside on Adoree' Jackson in three-receiver sets that push Logan Ryan into the slot. Jackson has given up a 70.6 catch rate and a 116.2 pa ser rating when teams throw in his direction downfield.

Titans vs. Chiefs prediction

The Titans have take advantage of the Patriots' and Ravens' offensive limitations the past two games. The Patriots couldn't get any big plays outside in the D.J. Wonnum Jerseys pa sing game; the Ravens saw their short-to-intermediate inside pa sing game taken away. The Chiefs can hurt the Titans both inside and outside with Mahomes, Kelce, Hill and several others. The Titans also are facing a good secondary who can keep them from jumping out to a lead with big plays there. Look for Kansas City to play from ahead by aggre sively attacking coverage weakne ses earlyto ensure Tenne see can't quite catch up with more needed from Tannehill than Henry.

Chiefs 34, Titans 27