Additionally, formulations of CBD and other medications are being developed that envelop the drug molecules with layers of fats called nanolipospheres which leads to enhanced absorption. Cmax and Tmax may be increased if CBD is accompanied by ingestion of piperine found in black pepper. Piperine has been found to reduce metabolic breakdown of CBD in the intestines and the liver. Furthermore, piperine may suppress the elimination of CBD from the brain by inhibiting the transporter mechanism involved, leading to prolonged effects of CBD and THC.
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